Evaluation of salivary osteocalcin level in smokers and non-smokers with dental implants: research article


Published: 5 October 2022
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Authors

  • V. Fakhrzadeh Tabriz University of Medical Sciences, Faculty of Dentistry, Department of Prosthodontics, Tabriz, Iran, Islamic Republic of.
  • H. Eslami Department of Oral and Maxillofacial Surgery, School of Dentistry, Tabriz University of Medical Science, Tabriz, Iran, Islamic Republic of.
  • F. Farhadi Shabestari Department of Oral and Maxillofacial Surgery, School of Dentistry, Tabriz University of Medical Science, Tabriz, Iran, Islamic Republic of.
  • M. Zohdi Student's Research committee, Tabriz University of Medical Sciences, Tabriz, Iran, Islamic Republic of.
  • B. Hasanalizadeh Department of Oral and Maxillofacial Surgery, School of Dentistry, Tabriz University of Medical Science, Tabriz, Iran, Islamic Republic of.
  • N. Yasamineh Dental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz, Iran, Islamic Republic of.

Aim The present study is designed to evaluate the salivary osteocalcin level of smokers and peer non-smokers to better understand the mechanisms involved in the effects of smoking on dental implants.

Methods The present clinical trial was conducted on saliva samples of patients with dental implants referring to the dentistry faculty of Tabriz University of Medical Sciences. Based on study inclusion and exclusion criteria, eligible patients were divided into two groups of smokers (case group) and non-smokers (control group), each including 35 patients. ELISA (enzyme-linked immune sorbent assay) kit was used to measure the salivary osteocalcin level.

Results were analyzed using descriptive statistical methods (mean±SD, frequency, percentage) and SPSS version 17.Results The salivary osteocalcin level is significantly lower in smokers compared with nonsmokers.

Conclusion Lower salivary osteocalcin level in smokers compared to nonsmokers may relate to bone resorption and high rate of dental implant failures in smokers


Fakhrzadeh, V., Eslami, H., Farhadi Shabestari, F., Zohdi, M., Hasanalizadeh, B., & Yasamineh, N. (2022). Evaluation of salivary osteocalcin level in smokers and non-smokers with dental implants: research article. Journal of Osseointegration, 14(4), 237–240. https://doi.org/10.23805/JO.2022.14.32

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